Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823843 | 1.00 | PTGS1 (0.55) | PTGS1PTGS2MAPK1ALDH1A1TSHR | |
| SCHEMBL10823844 | 1.00 | PTGS1 (0.55) | PTGS1PTGS2MAPK1ALDH1A1TSHR | |
| SCHEMBL2681671 | 0.84 | MAPK1 (0.57) | MAPK1ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL21125070 | 0.83 | PTGS1 (0.67) | PTGS1PTGS2ALDH1A1TSHRTDP1 | |
| SCHEMBL9308336 | 0.81 | MAPK1 (0.53) | MAPK1ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL15682380 | 0.81 | NPC1 (0.57) | MAPK1ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL9308347 | 0.81 | MAPK1 (0.53) | MAPK1ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL9308341 | 0.81 | MAPK1 (0.53) | MAPK1ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL3212678 | 0.79 | HSD17B10 (0.50) | PTGS1MAPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL10598869 | 0.78 | PTGS1 (0.62) | PTGS1PTGS2MAPK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110205-B1 | COLOURED LIQUID CRYSTAL MIXTURES CONTAINING PHENYL ETHANES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-12-09 | — | — | EP | disclosed |
| US-4613208-A | ELECTROOPTICS; ULTRAVIOLET RADIATION STABILITY; QUICK RESPONSE | HOFFMANN-LA ROCHE INC. (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0110205-A2 | Coloured liquid crystal mixtures containing phenyl ethanes | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-13 | — | — | EP | disclosed |