Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11188287 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL1866245 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL904462 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL6233586 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL30309327 | 0.94 | — | — | |
| Sulfuric Acid SCHEMBL7192079 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL7899793 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL64518 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL413613 | 0.94 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL1694361 | 0.89 | MEN1 (0.39) | MEN1ALDH1A1TSHRKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051215-B1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF 3-ARYL-3-HYDROXY-PHTHALIMIDINES | USV PHARMACEUTICAL CORPORATION (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4477675-A | SULFONATION OF A 3-PHENYLPHTHALIMIDINE; OXIDATION TO OBTAIN THE 3-HYDROXY DERIVATIVE | USV PHARMACEUTICAL CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4331600-A | 3-/HALOSULFONYL OR SULFAMYLPHENYL/PHTHALIMIDINE, HYPOTENSIVE AGENTS, DIURETICS | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| EP-0051215-A2 | Methods and intermediates for the synthesis of 3-aryl-3-hydroxy-phthalimidines | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |
| EP-0051217-A1 | Oxidation process | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |