Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791979 | 0.92 | TDP1 (0.57) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL11292712 | 0.90 | TDP1 (0.68) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL697205 | 0.88 | TDP1 (0.44) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL10792648 | 0.84 | TDP1 (0.51) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL703762 | 0.79 | TDP1 (0.44) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL10795101 | 0.79 | KMT2A (0.55) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL10795024 | 0.78 | CYP2D6 (0.62) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL697336 | 0.78 | BRD4 (0.49) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL695900 | 0.78 | TDP1 (0.54) | TDP1LMNAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL10790597 | 0.78 | CYP2D6 (0.59) | TDP1LMNAKMT2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |
| EP-0058047-A1 | Substituted imidazole derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-08-18 | — | — | EP | disclosed |