Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | FAP | Q12884 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793269 | 1.00 | NR1I2 (0.60) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10797301 | 1.00 | NR1I2 (0.60) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10797292 | 1.00 | NR1I2 (0.60) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10793834 | 0.92 | NR1I2 (0.62) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10792780 | 0.92 | NR1I2 (0.62) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10792786 | 0.92 | NR1I2 (0.62) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10793836 | 0.92 | NR1I2 (0.62) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10889846 | 0.92 | NR1I2 (0.59) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL10889844 | 0.92 | NR1I2 (0.59) | NR1I2HTR2CMAPTALDH1A1USP2 | |
| SCHEMBL9482056 | 0.91 | TDP1 (0.65) | NR1I2HTR2CMAPTALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | disclosed |