Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.58 |
| ▸ | LTA4H | P09960 | 3/20 | 0.58 |
| ▸ | ANPEP | P15144 | 3/20 | 0.58 |
| ▸ | ECE1 | P42892 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795023 | 1.00 | MME (0.58) | MMELTA4HANPEPECE1ACE | |
| SCHEMBL20549517 | 0.83 | MME (0.70) | MMELTA4HANPEP | |
| SCHEMBL18929434 | 0.83 | MME (0.70) | MMELTA4HANPEP | |
| SCHEMBL18929411 | 0.83 | MME (0.70) | MMELTA4HANPEP | |
| SCHEMBL20550160 | 0.83 | MME (0.70) | MMELTA4HANPEP | |
| SCHEMBL7369702 | 0.81 | ACE (0.58) | MMEECE1ACE | |
| SCHEMBL31516107 | 0.79 | MME (0.58) | MMELTA4HANPEP | |
| Hydrochloric Acid SCHEMBL5916385 | 0.79 | MME (0.55) | MMELTA4HANPEPECE1ACE | |
| SCHEMBL6928142 | 0.79 | MME (0.73) | MMEANPEP | |
| Bromide SCHEMBL6930154 | 0.78 | MME (0.72) | MMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |