Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796352 | 1.00 | KCNH2 (0.54) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10801146 | 0.91 | KCNH2 (0.51) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10801152 | 0.91 | KCNH2 (0.51) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10367999 | 0.90 | KCNH2 (0.52) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10367997 | 0.90 | KCNH2 (0.52) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10815953 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10815936 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10367567 | 0.89 | KCNH2 (0.53) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL10367571 | 0.89 | KCNH2 (0.53) | KCNH2TDP1APAF1TSHRLMNA | |
| SCHEMBL9623724 | 0.88 | KCNH2 (0.52) | KCNH2TDP1APAF1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639448-A | 7-amino-3-[substituted vinyl]-3-cephem-4-carboxylates having antimicrobial activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-01-27 | — | — | US | disclosed |
| US-4546101-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |