Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342950 | 1.00 | CA1 (0.57) | CA1CA2CA7CA9CSNK1E | |
| SCHEMBL31287893 | 1.00 | CA1 (0.57) | CA1CA2CA7CA9CSNK1E | |
| SCHEMBL31362241 | 1.00 | CA1 (0.57) | CA1CA2CA7CA9CSNK1E | |
| SCHEMBL10844759 | 1.00 | CA1 (0.57) | CA1CA2CA7CA9CSNK1E | |
| SCHEMBL9661280 | 1.00 | CA1 (0.57) | CA1CA2CA7CA9CSNK1E | |
| SCHEMBL9662621 | 0.98 | CA1 (0.58) | CA1CA2CA7CA9CSNK1E | |
| SCHEMBL10800338 | 0.88 | CA1 (0.51) | CA1CA2CA7CA9CSNK1E | |
| SCHEMBL14040676 | 0.87 | CA1 (0.64) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL10511102 | 0.87 | CA1 (0.64) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL23533573 | 0.86 | CSNK1E (0.49) | CA1CA2CA7CA9CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673672-A | ANTITUMOR AGENTS | SANDOZ PHARMACEUTICALS CORP. (US) | 1987-06-16 | — | — | US | disclosed |
| US-4619917-A | PLATELET ACTIVATING FACTOR INHIBITORS | SANDOZ PHARM. CORP. (US) | 1986-10-28 | — | — | US | disclosed |