Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.33 |
| ▸ | CTSD | P07339 | 5/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799377 | 0.92 | CYSLTR1 (0.39) | CYSLTR1CYSLTR2GRM2CTSDGPR84 | |
| SCHEMBL10974390 | 0.90 | CYSLTR1 (0.35) | CYSLTR1CYSLTR2GRM2CTSD | |
| SCHEMBL10798437 | 0.90 | CYSLTR1 (0.38) | CYSLTR1CYSLTR2GRM2CTSDGPR84 | |
| SCHEMBL10799118 | 0.85 | CYSLTR2 (0.38) | CYSLTR1CYSLTR2 | |
| SCHEMBL10798791 | 0.82 | CYSLTR1 (0.36) | CYSLTR1CYSLTR2GRM2CTSDGPR84 | |
| SCHEMBL10656630 | 0.81 | CYSLTR2 (0.40) | CYSLTR1CYSLTR2GRM2 | |
| SCHEMBL10750458 | 0.81 | CYSLTR2 (0.39) | CYSLTR1CYSLTR2GRM2 | |
| SCHEMBL10798804 | 0.80 | CYSLTR1 (0.35) | CYSLTR1CYSLTR2GRM2GPR84 | |
| SCHEMBL10726976 | 0.78 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2GRM2CTSD | |
| SCHEMBL10799322 | 0.76 | MEN1 (0.36) | CYSLTR1CYSLTR2GRM2CTSDGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132124-B1 | NOVEL PHARMACEUTICAL COMPOUNDS AND THEIR PREPARATION | Lilly Industries Limited (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0132124-A1 | Novel pharmaceutical compounds and their preparation | Lilly Industries Limited (GB) | 1985-01-23 | — | — | EP | disclosed |