Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174837 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL820078 | 0.96 | — | — | |
| SCHEMBL6244498 | 0.83 | CA1 (0.63) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL9558123 | 0.83 | CA1 (0.55) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL9393814 | 0.80 | CA1 (0.60) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL17075385 | 0.80 | TSHR (0.50) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL11262173 | 0.80 | CA1 (0.60) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL31439256 | 0.79 | TSHR (0.67) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL12158577 | 0.74 | TSHR (0.41) | TSHRALDH1A1LMNATP53CA1 | |
| SCHEMBL45244 | 0.74 | TSHR (0.71) | TSHRALDH1A1LMNATP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670163-A | HALOHYDROXYALKYLTHIO-SUBSTITUTED OR DIHYDROXYALKYLTHIO-SUBSTITUTED POLYCARBOXYLIC ACIDS AND SALTS | PHILLIPS PETROLEUM COMPANY (US) | 1987-06-02 | — | — | US | disclosed |