SCHEMBL10799482

SCHEMBL10799482

Nc1cc(I)cc(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 5/20 0.48
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
DDO Q99489 1/20 0.47
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 2/20 0.39
CA3 P07451 1/20 0.39
MAPT P10636 1/20 0.39
SELL P14151 1/20 0.39
HPGD P15428 1/20 0.39
SELP P16109 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223304 0.83 KDM4E (0.56) TPMTKDM4EALDH1A1LMNAMEN1
SCHEMBL422824 0.83 TPMT (0.59) TPMTKDM4EALDH1A1LMNAMEN1
SCHEMBL109155 0.83 KDM4E (0.56) TPMTKDM4EALDH1A1LMNAMEN1
SCHEMBL1951073 0.83 TPMT (0.59) TPMTKDM4EALDH1A1LMNACA12
SCHEMBL2820215 0.83 KDM4E (0.56) TPMTKDM4EALDH1A1LMNAMEN1
SCHEMBL17161232 0.82 CYP3A4 (0.38) KDM4EALDH1A1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL4295557 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1LMNAMEN1
Water SCHEMBL2806532 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1LMNAMEN1
Water SCHEMBL17938300 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1LMNAMEN1
SCHEMBL2888306 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106457160-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-10-08 CN disclosed
US-20170065938-A1 COMPOSITE POLYAMIDE MEMBRANE POST-TREATED WITH NITROUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-09 US disclosed
CN-106457160-A Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2017-02-22 CN disclosed
WO-2015175254-A1 COMPOSITE POLYAMIDE MEMBRANE POST-TREATED WITH NITROUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-19 WO disclosed
US-4642240-A LOW CALORIE SWEETENERS GENERAL FOODS CORPORATION (US) 1987-02-10 US disclosed