Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10803437 | 1.00 | PRMT1 (0.43) | PRMT1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10799619 | 0.99 | PRMT1 (0.42) | PRMT1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10799624 | 0.99 | PRMT1 (0.42) | PRMT1MAPTALDH1A1SMN1; SMN2HTT | |
| Perchlorate SCHEMBL10801690 | 0.77 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| Perchlorate SCHEMBL10801698 | 0.77 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| Iodide SCHEMBL10801669 | 0.75 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| Iodide SCHEMBL10801672 | 0.75 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| Iodide SCHEMBL3053673 | 0.74 | MAPT (0.58) | PRMT1MAPTALDH1A1SMN1; SMN2HTT | |
| Perchlorate SCHEMBL10815942 | 0.73 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| Perchlorate SCHEMBL10815949 | 0.73 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4713316-A | INFRARED SENSITIZING DYES, MOBILE DYE PRECURSORS, ALKALI, SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |