Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.72 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.72 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.72 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | TOP2A | P11388 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811007 | 0.92 | PIK3CG (0.78) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10811186 | 0.92 | KDM4E (0.72) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10818691 | 0.89 | PIK3CG (0.81) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10810244 | 0.88 | PIK3CG (0.59) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL825059 | 0.86 | KDM4E (0.92) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10809240 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10807306 | 0.86 | KDM4E (0.81) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL29350842 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10920267 | 0.86 | KDM4E (0.73) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL10920123 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117473-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0121727-B1 | BACTERICIDAL AGENT BASED ON QUINOLONECARBOXYLIC ACIDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| US-4559341-A | Quinolonecarboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | disclosed |
| EP-0121727-A1 | Bactericidal agent based on quinolonecarboxylic acids | BAYER AG (DE) | 1984-10-17 | — | — | EP | disclosed |
| EP-0117473-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |