Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814850 | 0.82 | HSP90AA1 (0.48) | HSP90AA1CSNK2A1MEN1KMT2ACA1 | |
| SCHEMBL130505 | 0.78 | CSNK2A1 (0.57) | CSNK2A1MEN1KMT2ACA1CA2 | |
| SCHEMBL10813935 | 0.77 | KCNH2 (0.50) | HSP90AA1CSNK2A1MEN1KMT2ACA1 | |
| SCHEMBL2636194 | 0.76 | NAPRT (0.59) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL2636255 | 0.71 | KDM4E (0.46) | MEN1KMT2APTGS2ALDH1A1HPGD | |
| SCHEMBL3409151 | 0.71 | CHRM5 (0.68) | MEN1KMT2AALDH1A1KDM4EALOX15 | |
| SCHEMBL10812471 | 0.71 | CYP3A4 (0.44) | HSP90AA1MEN1KMT2ACA1CA2 | |
| SCHEMBL727925 | 0.70 | MCL1 (0.55) | CSNK2A1MEN1KMT2ACA1CA2 | |
| SCHEMBL3742173 | 0.70 | CSNK2A1 (0.67) | CSNK2A1MEN1KMT2ACA1CA2 | |
| SCHEMBL1520808 | 0.70 | MEN1 (0.61) | CSNK2A1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114734-B1 | PYRIDINYLMETHYLAMINO-ARYLIC ACIDS | THE UPJOHN COMPANY (US) | 1987-05-13 | — | — | EP | claimed |
| US-4486593-A | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors | THE UPJOHN COMPANY (US) | 1984-12-04 | — | — | US | claimed |
| EP-0114734-A2 | Pyridinylmethylamino-arylic acids | THE UPJOHN COMPANY (US) | 1984-08-01 | — | — | EP | claimed |
| EP-0114734-B1 | PYRIDINYLMETHYLAMINO-ARYLIC ACIDS | THE UPJOHN COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |
| EP-0114734-A2 | Pyridinylmethylamino-arylic acids | THE UPJOHN COMPANY (US) | 1984-08-01 | — | — | EP | disclosed |