Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.38 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169863 | 0.93 | CYP2C19 (0.69) | CYP2C19SMN1; SMN2CYP3A4TSHRSRC | |
| SCHEMBL28074568 | 0.84 | CYP2C19 (0.60) | CYP2C19SMN1; SMN2CA1CA2CES2 | |
| SCHEMBL17350200 | 0.84 | TSHR (0.64) | CYP2C19SMN1; SMN2CYP3A4TSHRSRC | |
| SCHEMBL20315397 | 0.82 | SMN1; SMN2 (0.58) | CYP2C19SMN1; SMN2CYP3A4TSHRSRC | |
| SCHEMBL28032276 | 0.82 | CYP2C19 (0.58) | CYP2C19SMN1; SMN2CYP3A4TSHRSRC | |
| SCHEMBL28074473 | 0.82 | CYP2C19 (0.58) | CYP2C19SMN1; SMN2CYP3A4TSHRSRC | |
| SCHEMBL29223361 | 0.82 | CYP2C19 (0.58) | CYP2C19SMN1; SMN2CYP3A4TSHRBLM | |
| SCHEMBL28031670 | 0.81 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2BLM | |
| SCHEMBL1363549 | 0.81 | SRC (0.67) | CYP2C19SMN1; SMN2SRCKDM4E | |
| SCHEMBL17626462 | 0.79 | SRC (0.64) | CYP2C19SMN1; SMN2SRCACP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074594-B1 | A THERMOPLASTIC TERNARY MOLDING COMPOSITION OF POLYURETHANE POLYPHOSPHONATES AND POLYCARBONATE RESINS | MOBAY CORPORATION (US) | 1987-10-14 | — | — | EP | disclosed |
| EP-0074594-A1 | A thermoplastic ternary molding composition of polyurethane polyphosphonates and polycarbonate resins | MOBAY CORPORATION (US) | 1983-03-23 | — | — | EP | disclosed |