Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 6/20 | 0.58 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FHIT | P49789 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759681 | 0.83 | DRD4 (0.70) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL8583590 | 0.82 | DRD4 (1.00) | DRD4DRD2DRD3ALDH1A1HPGD | |
| SCHEMBL11380048 | 0.81 | DRD4 (0.66) | DRD4DRD2DRD3MAOAMAOB | |
| Hydrochloric Acid SCHEMBL10816670 | 0.80 | DRD4 (0.65) | DRD4DRD2DRD3MAOAMAOB | |
| Hydrochloric Acid SCHEMBL10814338 | 0.80 | DRD4 (0.65) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL10813145 | 0.79 | DRD4 (0.66) | DRD4DRD2DRD3ALDH1A1HPGD | |
| SCHEMBL10813758 | 0.79 | DRD4 (0.64) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL10813959 | 0.79 | DRD4 (0.64) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL10817679 | 0.78 | ERN1 (0.53) | DRD4DRD2DRD3MAOAMAOB | |
| SCHEMBL10815168 | 0.77 | DRD4 (0.72) | DRD4DRD2DRD3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087280-B1 | 3-(2-MONO-AND DIALKYLAMINO)PROPYL(-1,2,3,4-TETRAHYDRO-5H-(1) BENZOPYRANO(3,4-C)PYRIDIN-5-ONES AND DERIVATIVES THEREOF, A PROCESS FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| EP-0087280-A2 | 3-(2-Mono-and dialkylamino)propyl(-1,2,3,4-tetrahydro-5H-(1) benzopyrano(3,4-c)pyridin-5-ones and derivatives thereof, a process for their production, and pharmaceutical compositions containing such compounds | WARNER-LAMBERT COMPANY (US) | 1983-08-31 | — | — | EP | disclosed |
| US-4382939-A | 3-[2-(Mono-and dialkylamino)propyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-C]pyridin-5-ones useful for treating bronchospastic diseases | WARNER LAMBERT COMPANY (US) | 1983-05-10 | — | — | US | disclosed |