Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CDA | P32320 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5911861 | 0.99 | MAPT (0.56) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL12071279 | 0.99 | MAPT (0.56) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL5911672 | 0.99 | MAPT (0.56) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL5911675 | 0.99 | MAPT (0.56) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL5911868 | 0.99 | MAPT (0.56) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL11070054 | 0.99 | MAPT (0.56) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL5912634 | 0.91 | MAPT (0.49) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL5911833 | 0.91 | MAPT (0.49) | MAPTCDAADORA3TP53LMNA | |
| SCHEMBL7597505 | 0.89 | MAPT (0.42) | MAPTCDAADORA3TP53BLM | |
| SCHEMBL5912623 | 0.88 | MAPT (0.44) | MAPTCDAADORA3TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100363-B1 | NITROIMIDAZOLE RADIOSENSITIZERS AND PHARMACEUTICAL COMPOSITIONS THEREOF | Research Corporation (US) | 1987-05-06 | — | — | EP | disclosed |