Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 10/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | EP300 | Q09472 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817743 | 0.84 | MAPK1 (0.80) | MAPK1BAZ2BCREBBPBRD4EP300 | |
| SCHEMBL2982055 | 0.83 | MAPK1 (0.78) | MAPK1BAZ2BCREBBPBRD4MET | |
| SCHEMBL2979198 | 0.83 | MAPK1 (0.78) | MAPK1BAZ2BCREBBPBRD4EP300 | |
| SCHEMBL10805635 | 0.83 | MAPK1 (1.00) | MAPK1BAZ2BCREBBPBRD4EP300 | |
| SCHEMBL2977735 | 0.83 | MAPK1 (0.78) | MAPK1CREBBPBRD4METEP300 | |
| SCHEMBL10818694 | 0.83 | MAPK1 (0.77) | MAPK1BAZ2BCREBBPBRD4EP300 | |
| SCHEMBL2980674 | 0.83 | MAPK1 (0.61) | MAPK1BAZ2BCREBBPBRD4MET | |
| SCHEMBL10801839 | 0.82 | MAPK1 (0.76) | MAPK1CREBBPBRD4EP300NPC1 | |
| SCHEMBL10818381 | 0.81 | MAPK1 (0.74) | MAPK1CREBBPBRD4METEP300 | |
| SCHEMBL14787916 | 0.81 | MAPK1 (0.74) | MAPK1BAZ2BCREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |