Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CAD | P27708 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817860 | 1.00 | NPSR1 (0.47) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL7379614 | 0.86 | NPSR1 (0.48) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL7379617 | 0.86 | NPSR1 (0.48) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL7902951 | 0.80 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL2647130 | 0.80 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL2647184 | 0.80 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL10966894 | 0.80 | TSHR (0.38) | NPSR1HCAR2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL6539020 | 0.79 | HCAR2 (0.40) | HCAR2 | |
| SCHEMBL11134387 | 0.79 | HCAR2 (0.40) | HCAR2 | |
| SCHEMBL6539016 | 0.79 | HCAR2 (0.40) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063747-B1 | 2-SUBSTITUTED OR UNSUBSTITUTED AMINOCARBONYLOXYALKYL-1,4-DIHYDROPYRIDINES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-12-09 | — | — | EP | disclosed |
| EP-0063359-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1985-12-11 | — | — | EP | disclosed |
| US-4404378-A | HYPOTENSIVE AGENTS; VASODILATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0063747-A1 | 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-11-03 | — | — | EP | disclosed |
| EP-0063359-A1 | 1,4-Dihydropyridine derivatives and processes for preparing the same | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-10-27 | — | — | EP | disclosed |