SCHEMBL10818399

SCHEMBL10818399

C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)N[C@@H]1CC(=O)Sc1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428568 0.88 ELANE (0.30) ELANE
SCHEMBL11089658 0.82
SCHEMBL5173742 0.81 MAPT (0.31)
SCHEMBL22406974 0.81 MAPT (0.31)
SCHEMBL9083649 0.81 MAPT (0.31)
SCHEMBL10416099 0.81 MAPT (0.31)
SCHEMBL9726025 0.81 MAPT (0.31)
SCHEMBL22406976 0.81 MAPT (0.31)
SCHEMBL10416083 0.81 MAPT (0.31)
SCHEMBL5173738 0.81 MAPT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0102239-B1 AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS INTERMEDIATES IN THE PREPARATION OF CARBAPENEM ANTIBIOTICS SANKYO COMPANY LIMITED (JP) 1987-10-14 EP disclosed
EP-0102239-A1 Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics SANKYO COMPANY LIMITED (JP) 1984-03-07 EP disclosed