Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.77 |
| ▸ | APAF1 | O14727 | 2/20 | 0.77 |
| ▸ | APEX1 | P27695 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.77 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.77 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.76 |
| ▸ | MMP2 | P08253 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482326 | 0.96 | TDP1 (0.75) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL9743881 | 0.96 | TDP1 (0.75) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL5248715 | 0.94 | TDP1 (0.82) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL6416850 | 0.94 | TDP1 (0.82) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL8673690 | 0.94 | TDP1 (0.82) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL8673686 | 0.94 | TDP1 (0.82) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL8651470 | 0.88 | TDP1 (0.73) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL9482360 | 0.88 | TDP1 (0.85) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL9482371 | 0.88 | TDP1 (0.85) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL9481450 | 0.88 | TDP1 (0.87) | TDP1APAF1APEX1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030630-B1 | 7-ACYLAMINO-3-VINYLCEPHALOSPORANIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM; THEIR STARTING COMPOUNDS AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-01 | — | — | EP | disclosed |