Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1081998

O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.[C]=O.[Ru].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
CES1 P23141 6/20 0.43
CPA1 P15085 1/20 0.36
CYP1A2 P05177 1/20 0.34
FAAH O00519 3/20 0.33
HDAC6 Q9UBN7 2/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL27516099 0.96 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL8364947 0.94 CYP3A4 (0.57) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL27963324 0.94 CYP3A4 (0.57) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL18425261 0.91 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL27870901 0.91 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL27511572 0.91 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL11783673 0.91 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL30195537 0.91 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL31532238 0.91 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL9798368 0.86 TDP1 (0.48) CYP3A4TDP1ESR1ESR2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011003029-A2 CATALYTIC DISPROPORTIONATION AND CATALYTIC REDUCTION OF CARBON-CARBON AND CARBON-OXYGEN BONDS OF LIGNIN AND OTHER ORGANIC SUBSTRATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-06 WO disclosed
US-H918-H DECARBONYLATION AND DEHYDROGENATION OF CARBOHYDRATES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1991-05-07 US disclosed