Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | VDR | P11473 | 9/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14523027 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL817082 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL817094 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL10125598 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL4903376 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL814645 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL4787102 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL14112429 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL814138 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 | |
| SCHEMBL13790311 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCYP19A1VDRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831161-B1 | MEDICAL AND COSMETIC USES OF 2-METHYLENE-19-NOR-(20R)-1-ALPHA-HYDROXY-BISHOMOPREGNACALCIFEROL | WISCONSIN ALUMNI RES FOUND (US) | 2017-07-26 | — | — | EP | disclosed |
| US-8222235-B2 | 2-methylene-19-nor-(20R)-1α-hydroxy-bishomopregnacalciferol | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-17 | — | — | US | disclosed |
| US-8222235-B2 | 2-methylene-19-nor-(20R)-1α-hydroxy-bishomopregnacalciferol | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-17 | — | — | US | disclosed |