SCHEMBL1082121

SCHEMBL1082121

CCCCCCCCC(CCCCCCCC)Oc1ccccc1/C=C/C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.50
PTGER4 P35408 2/20 0.48
PTGER3 P43115 2/20 0.48
PTGER2 P43116 2/20 0.48
GAA P10253 2/20 0.48
PTGER1 P34995 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 3/20 0.45
NFE2L2 Q16236 2/20 0.43
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
TFEB P19484 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
NFKB1 P19838 1/20 0.42
CA4 P22748 1/20 0.42
NPC1 O15118 1/20 0.42
BCHE P06276 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167061 0.95 HTT (0.48) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL9402728 0.95 HTT (0.48) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL9402737 0.95 HTT (0.48) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL5175460 0.86 HTT (0.58) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL4331860 0.83 PTGER1 (0.59) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL242465 0.83 PTGER1 (0.59) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL9402733 0.83 PTGER1 (0.59) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL9716933 0.83 PTGER1 (0.59) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL4331862 0.83 PTGER1 (0.59) HTTPTGER4PTGER3PTGER2GAA
SCHEMBL9716995 0.83 PTGER1 (0.59) HTTPTGER4PTGER3PTGER2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3087970-B1 WATER-IN-OIL EMULSIFIED SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2018-05-23 EP claimed
EP-2481393-B1 SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2016-11-02 EP claimed
EP-1618870-B1 Process for photostabilising a dibenzoylmethane derivative with an arylalkyl benzoate derivative and sunscreen compositions OREAL (FR) 2012-12-26 EP claimed
EP-1618870-A1 Process for photostabilising a dibenzoylmethane derivative with an arylalkyl benzoate derivative and sunscreening cosmetic compositions L'OREAL (FR) 2006-01-25 EP claimed
EP-0509426-B1 Process for the preparation of octyl methoxy cinnamate GIULINI CHEMIE (DE) 1997-03-19 EP claimed
EP-1618870-B1 Process for photostabilising a dibenzoylmethane derivative with an arylalkyl benzoate derivative and sunscreen compositions OREAL (FR) 2012-12-26 EP disclosed
WO-2011004293-A1 METHOD FOR PREPARING POLYMERIZED LIPID CONSTRUCTS, RESULTING POLYMERIZED LIPID CONSTRUCTS, AND USES THEREOF FOR ENCAPSULATING ACTIVE AGENTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-01-13 WO disclosed
EP-1618870-A1 Process for photostabilising a dibenzoylmethane derivative with an arylalkyl benzoate derivative and sunscreening cosmetic compositions L'OREAL (FR) 2006-01-25 EP disclosed
EP-1618870-A1 Process for photostabilising a dibenzoylmethane derivative with an arylalkyl benzoate derivative and sunscreening cosmetic compositions L'OREAL (FR) 2006-01-25 EP disclosed
EP-0988027-A1 COSMETIC COMPOSITION COMPRISING A FUNCTIONALISED POLYORGANOSILOXANE RHODIA CHIMIE (FR) 2000-03-29 EP disclosed
WO-1999006018-A1 COSMETIC COMPOSITION COMPRISING A FUNCTIONALISED POLYORGANOSILOXANE RHODIA CHIMIE (FR) 1999-02-11 WO disclosed
EP-0859589-A1 SKIN MOISTURIZING AND PROTECTIVE COSMETIC COMPOSITIONS Industria E Comércio de Cosméticos Natura Ltda (BR) 1998-08-26 EP disclosed
WO-1998001107-A1 SKIN MOISTURIZING AND PROTECTIVE COSMETIC COMPOSITIONS Indústria e Comércio de Cosméticos Natura Ltda. (BR) 1998-01-15 WO disclosed
EP-0609131-B1 Homogeneous composition based on fluorinated compounds and glycols, process of preparation and use in cosmetics OREAL (FR) 1997-12-17 EP disclosed
EP-0625039-B1 PREPARATION FOR SKIN USE COSMETICS DEV CO LTD (GB) 1995-09-20 EP disclosed
EP-0625039-A1 PREPARATION FOR SKIN USE. COSMETICS DEV CO LTD (GB) 1994-11-23 EP disclosed
EP-0609131-A1 Homogeneous composition based on fluorinated compounds and glycols, process of preparation and use in cosmetics L'OREAL (FR) 1994-08-03 EP disclosed
WO-1993013742-A1 PREPARATION FOR SKIN USE COSMETICS DEVELOPMENT COMPANY LIMITED (GB) 1993-07-22 WO disclosed