Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822579 | 1.00 | PTGER4 (0.38) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10822488 | 1.00 | PTGER4 (0.38) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10822490 | 1.00 | PTGER4 (0.38) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10822486 | 1.00 | PTGER4 (0.38) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10822402 | 0.86 | AOC3 (0.41) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10822404 | 0.86 | AOC3 (0.41) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10822422 | 0.83 | HDAC6 (0.36) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10822331 | 0.83 | HDAC6 (0.36) | PTGER4HDAC4HDAC6KDM4EAOC3 | |
| SCHEMBL10727779 | 0.81 | ADRB3 (0.44) | HDAC4HDAC6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10727788 | 0.81 | ADRB3 (0.44) | HDAC4HDAC6KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585796-A | HYPOGLYCEMIC, ANTI-OBESITY | HOFFMANN-LA ROCHE INC. (US) | 1986-04-29 | — | — | US | disclosed |