Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | IDH1 | O75874 | 16/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823776 | 0.92 | PRMT1 (0.71) | PRMT1IDH1CASP6 | |
| SCHEMBL10823606 | 0.87 | PRMT1 (0.66) | PRMT1IDH1 | |
| SCHEMBL10823767 | 0.86 | PRMT1 (0.55) | PRMT1IDH1 | |
| SCHEMBL10900036 | 0.85 | PRMT1 (0.81) | PRMT1NT5ENSD2DUSP3PTPN5 | |
| SCHEMBL29384348 | 0.85 | PRMT1 (0.81) | PRMT1NT5ENSD2DUSP3PTPN5 | |
| SCHEMBL10823410 | 0.84 | IDH1 (0.61) | IDH1 | |
| SCHEMBL10823426 | 0.84 | IDH1 (0.58) | IDH1 | |
| SCHEMBL10823509 | 0.84 | IDH1 (0.58) | IDH1 | |
| SCHEMBL10823488 | 0.84 | PRMT1 (0.64) | PRMT1NT5ENSD2DUSP3PTPN5 | |
| SCHEMBL10823432 | 0.83 | IDH1 (0.59) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |