Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.73 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | CASP6 | P55212 | 2/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823628 | 0.95 | PRMT1 (0.78) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL10823632 | 0.91 | PRMT1 (0.60) | PRMT1SIRT1CASP6NT5ENSD2 | |
| SCHEMBL10823345 | 0.88 | PRMT1 (0.67) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL10823488 | 0.86 | PRMT1 (0.64) | PRMT1SIRT1CASP6NT5ENSD2 | |
| SCHEMBL10823606 | 0.85 | PRMT1 (0.66) | PRMT1SIRT1 | |
| SCHEMBL29349608 | 0.85 | PRMT1 (1.00) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL6079067 | 0.85 | PRMT1 (1.00) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL2679101 | 0.85 | PRMT1 (1.00) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL6079153 | 0.84 | PRMT1 (0.72) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL6078726 | 0.84 | PRMT1 (0.72) | PRMT1SIRT1CASP6CTDSP1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |