Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 8/20 | 0.85 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.85 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.85 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | THPO | P40225 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823949 | 0.99 | CACNA1F (0.87) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10824020 | 0.99 | CACNA1F (0.87) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10823994 | 0.99 | CACNA1F (0.87) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7275184 | 0.93 | CACNA1F (0.82) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10900412 | 0.92 | CACNA1F (1.00) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10902151 | 0.92 | CACNA1F (1.00) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10902559 | 0.92 | CACNA1F (1.00) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10899725 | 0.92 | CACNA1F (1.00) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10899754 | 0.92 | CACNA1F (1.00) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL3435816 | 0.92 | CACNA1F (0.88) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565824-A | Certain nitratoalkyl ester dihydropyridines having antihypertensive properties | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-21 | — | — | US | disclosed |