Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 1.00 |
| ▸ | IAPP | P10997 | 5/20 | 0.88 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369293 | 1.00 | APP (1.00) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL21133739 | 1.00 | APP (1.00) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL10826170 | 1.00 | APP (1.00) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL10826172 | 1.00 | APP (1.00) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL8847524 | 0.98 | APP (0.97) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL9681899 | 0.98 | APP (0.97) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL29080020 | 0.92 | APP (0.85) | APPIAPPPTGS1TTRDPP4 | |
| SCHEMBL9363805 | 0.90 | APP (0.82) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL28959762 | 0.90 | APP (0.82) | APPIAPPHTR1APTGS1TTR | |
| SCHEMBL9363841 | 0.90 | APP (0.82) | APPIAPPHTR1APTGS1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618627-A | ALLERGIES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0125919-A2 | Catechol derivatives, their production and intermediates therefor, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |