Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 13/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10830115 | 0.92 | ABCB1 (0.55) | ABCB1MAPK1TSHRRAB9AHSD17B10 | |
| SCHEMBL10829982 | 0.92 | MAPK1 (0.55) | ABCB1MAPK1TSHRRAB9AHSD17B10 | |
| SCHEMBL10829711 | 0.90 | MEN1 (0.56) | ABCB1MAPK1TSHRRAB9ACYP2D6 | |
| SCHEMBL10830784 | 0.90 | POLB (0.53) | ABCB1MAPK1TSHRRAB9AHSD17B10 | |
| SCHEMBL10830277 | 0.90 | ABCB1 (0.51) | ABCB1MAPK1TSHRCYP2D6HIF1A | |
| SCHEMBL10829678 | 0.89 | ABCB1 (0.52) | ABCB1MAPK1TSHRRAB9AHSD17B10 | |
| SCHEMBL10830014 | 0.88 | ABCB1 (0.48) | ABCB1MAPK1TSHRRAB9AHSD17B10 | |
| SCHEMBL10830651 | 0.87 | ABCB1 (0.48) | ABCB1MAPK1 | |
| SCHEMBL10830019 | 0.86 | ABCB1 (0.55) | ABCB1GRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL10830049 | 0.85 | ABCB1 (0.48) | ABCB1MAPK1TSHRCYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4571409-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1986-02-18 | — | — | US | disclosed |
| EP-0075207-B1 | AMINOPROPANOL DERIVATIVES OF 2-HYDROXY-BETA-PHENYL PROPIOPHENONES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1986-02-05 | — | — | EP | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0075207-A2 | Aminopropanol derivatives of 2-hydroxy-beta-phenyl propiophenones, processes for their preparation and therapeutic agents containing them | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |