Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17580059 | 0.83 | S1PR1 (0.45) | S1PR1SKP2 | |
| SCHEMBL14268146 | 0.81 | CNR1 (0.45) | S1PR1SKP2 | |
| SCHEMBL24620667 | 0.81 | S1PR1 (0.41) | S1PR1SKP2 | |
| SCHEMBL31574000 | 0.80 | SKP2 (0.44) | TDP1SKP2MEN1KMT2A | |
| SCHEMBL4074762 | 0.80 | SKP2 (0.44) | TDP1SKP2MEN1KMT2A | |
| SCHEMBL17471715 | 0.79 | KDM4E (0.47) | S1PR1TDP1 | |
| SCHEMBL26586585 | 0.79 | S1PR1 (0.40) | S1PR1SKP2 | |
| SCHEMBL19559097 | 0.79 | TAAR1 (0.45) | S1PR1 | |
| SCHEMBL11856257 | 0.77 | TAAR1 (0.41) | TDP1SKP2MEN1KMT2A | |
| SCHEMBL17471720 | 0.76 | CYP4A11 (0.41) | S1PR1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633026-A | DEHYDROHALOGENATION OF RING-HALOGENATED ALPHA- OR BETA-BROMOETHYL BENZENES WITH STRONG BASE, POLYOXYETHYLENE GLYCOL CATALYST, AMINE POLYMERIZATION INHIBITOR | ETHYL CORPORATION (US) | 1986-12-30 | — | — | US | disclosed |