Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891757 | 0.85 | TSHR (0.50) | TSHRALDH1A1KDM4ECETPMAPK1 | |
| SCHEMBL10832549 | 0.85 | TSHR (0.58) | TSHRALDH1A1KDM4ECETPMAPK1 | |
| SCHEMBL13711507 | 0.84 | TSHR (0.57) | TSHRALDH1A1KDM4ECETPMAPK1 | |
| SCHEMBL13892565 | 0.83 | TSHR (0.56) | TSHRALDH1A1KDM4ECETPMAPK1 | |
| SCHEMBL10832590 | 0.82 | TSHR (0.55) | TSHRALDH1A1KDM4ECETPMAPK1 | |
| SCHEMBL11228462 | 0.80 | TSHR (0.53) | TSHRALDH1A1CETPMAPK1FOLH1 | |
| SCHEMBL13596714 | 0.80 | TSHR (0.57) | TSHRALDH1A1KDM4ECETPMAPK1 | |
| SCHEMBL23732772 | 0.78 | TSHR (0.60) | TSHRALDH1A1KDM4ECETPMAPK1 | |
| SCHEMBL9052482 | 0.78 | TSHR (0.59) | TSHRALDH1A1CETPFOLH1SRC | |
| SCHEMBL5669129 | 0.78 | TSHR (0.55) | TSHRALDH1A1CETPMAPK1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613674-A | FIREPROOFING | TSOLIS ALEXANDROS K | 1986-09-23 | — | — | US | disclosed |
| US-4431596-A | REACTING GLYOXAL WITH PHOSPHOROUS ACID COMPOUNDS | TSOLIS ALEXANDROS K | 1984-02-14 | — | — | US | disclosed |