Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SETD1B | Q9UPS6 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473813 | 0.85 | GAA (0.59) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL1180075 | 0.83 | KDM4E (0.62) | SMN1; SMN2KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL18263533 | 0.82 | GAA (0.68) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL18263445 | 0.82 | SMN1; SMN2 (0.58) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL12905265 | 0.81 | MCL1 (0.57) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL6743288 | 0.81 | TP53 (0.62) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL18263421 | 0.81 | TP53 (0.58) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL335256 | 0.80 | KDM4E (0.60) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL10359383 | 0.80 | TP53 (0.66) | GAATP53MCL1NPC1SMN1; SMN2 | |
| SCHEMBL6474483 | 0.80 | MCL1 (0.56) | GAATP53MCL1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598085-A | Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-07-01 | — | — | US | disclosed |
| US-4518612-A | Naphthalene and 2-oxo-benzopyran acids and derivatives and pharamaceutical use thereof | FISONS PLC (GB) | 1985-05-21 | — | — | US | disclosed |
| US-4424231-A | Compounds | FISONS LIMITED (GB) | 1984-01-03 | — | — | US | disclosed |
| EP-0061800-A1 | Anti SRS-A carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them | FISONS plc (GB) | 1982-10-06 | — | — | EP | disclosed |