Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834238 | 1.00 | MAPT (0.56) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL10834457 | 0.84 | MEN1 (0.50) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL10834454 | 0.84 | MEN1 (0.50) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6812010 | 0.84 | MEN1 (0.60) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6812006 | 0.84 | MEN1 (0.60) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL10834369 | 0.80 | NPSR1 (0.45) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL10834374 | 0.80 | NPSR1 (0.45) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL13905008 | 0.78 | MEN1 (0.59) | MAPTL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10834890 | 0.76 | MAPT (0.49) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL10834891 | 0.76 | MAPT (0.49) | MAPTPOLBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628083-A | ANTIFERTILITY ENZYME INHIBITOR, PROSTAGLANDIN INFLUENCE | PHARMACIA AB (SE) | 1986-12-09 | — | — | US | disclosed |
| EP-0021229-B1 | ARYLAZO COMPOUNDS, THEIR PREPARATION AND THEIR USE | PHARMACIA AB (SE) | 1982-12-22 | — | — | EP | disclosed |
| EP-0021229-A1 | Arylazo compounds, their preparation and their use | PHARMACIA AB (SE) | 1981-01-07 | — | — | EP | disclosed |