Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.46 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
| ▸ | APEX1 | P27695 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834727 | 1.00 | NR1I2 (0.46) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL9602475 | 0.90 | NR1I2 (0.47) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL9602482 | 0.90 | NR1I2 (0.47) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL9463399 | 0.83 | NR1I2 (0.43) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL10834739 | 0.82 | TDP1 (0.34) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL10778514 | 0.82 | NR1I2 (0.53) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL9865111 | 0.82 | NR1I2 (0.53) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL9462688 | 0.81 | KMT2A (0.40) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL9703664 | 0.80 | NR1I2 (0.50) | NR1I2PGRHTR2CPPARGSLC22A6 | |
| SCHEMBL9703667 | 0.80 | NR1I2 (0.50) | NR1I2PGRHTR2CPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4607054-A | Antiandrogenic compositions containing indene-7-ones | ROUSSEL UCLAF (FR) | 1986-08-19 | — | — | US | claimed |
| EP-0112164-A2 | Cephem compounds, and their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |