Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835051 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10834302 | 0.92 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10835195 | 0.90 | TDP1 (0.60) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10835169 | 0.90 | TDP1 (0.60) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10834805 | 0.79 | TDP1 (0.52) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10834313 | 0.79 | TDP1 (0.52) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11325928 | 0.78 | TDP1 (0.53) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11191436 | 0.75 | TDP1 (0.55) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11191440 | 0.75 | TDP1 (0.55) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11416758 | 0.73 | TDP1 (0.60) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567199-A | SOIL INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-28 | — | — | US | disclosed |