Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 14/20 | 0.69 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.69 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284052 | 1.00 | LPAR3 (0.69) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL3814362 | 1.00 | LPAR3 (0.69) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL1123899 | 1.00 | LPAR3 (0.69) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL1123777 | 1.00 | LPAR3 (0.69) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL14968993 | 0.98 | LPAR3 (0.65) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL3670692 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL29222525 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL27873429 | 0.93 | LPAR3 (0.72) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL3825124 | 0.92 | LPAR3 (0.66) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL10337001 | 0.92 | LPAR3 (0.66) | LPAR3LPAR2LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61159439-A | — | — | None | — | — | JP | disclosed |
| JP-S61159439-A | HALOGEN-CONTAINING RESIN COMPOSITION | SHIN ETSU CHEM CO LTD | 1986-07-19 | — | — | JP | disclosed |