Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15151965 | 0.95 | TSHR (0.42) | TSHRCYP3A4HTTUSP2SPHK1 | |
| Triethylene Glycol SCHEMBL10835139 | 0.90 | TSHR (0.63) | TSHRCYP3A4HTTMAPTMEN1 | |
| SCHEMBL13315991 | 0.81 | TSHR (0.48) | TSHRCYP3A4HTTMAPTMEN1 | |
| SCHEMBL29030314 | 0.81 | TSHR (0.48) | TSHRCYP3A4HTTMAPTMEN1 | |
| SCHEMBL10206898 | 0.80 | CYP3A4 (0.40) | TSHRCYP3A4HTTUSP2SPHK1 | |
| SCHEMBL27826106 | 0.79 | CYP3A4 (0.42) | TSHRCYP3A4HTTUSP2SPHK1 | |
| SCHEMBL27826094 | 0.79 | TSHR (0.46) | TSHRCYP3A4HTTMAPTMEN1 | |
| SCHEMBL20023894 | 0.78 | CYP3A4 (0.39) | TSHRCYP3A4HTTUSP2SPHK1 | |
| SCHEMBL11466654 | 0.77 | HSD17B10 (0.67) | TSHRCYP3A4HTTMAPTMEN1 | |
| SCHEMBL232613 | 0.77 | HSD17B10 (0.67) | TSHRCYP3A4HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579992-A | DEHYDROCHLORINATION OF CHLORO-ALKANES | HUELS AKTIENGESELLSCHAFT (DE) | 1986-04-01 | — | — | US | claimed |