Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573659 | 0.94 | NR1I2 (0.52) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL10805534 | 0.94 | NR1I2 (0.52) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9573648 | 0.94 | NR1I2 (0.52) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9204298 | 0.94 | NR1I2 (0.51) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9370289 | 0.94 | NR1I2 (0.51) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL10910303 | 0.92 | NR1I2 (0.60) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9513501 | 0.92 | NR1I2 (0.49) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9513492 | 0.92 | NR1I2 (0.49) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL10953548 | 0.91 | NR1I2 (0.51) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9515800 | 0.91 | TDP1 (0.49) | NR1I2PPARGPGRESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4621081-A | Cephalosporin antibiotics | GLAXO GROUP LIMITED (GB) | 1986-11-04 | — | — | US | disclosed |
| US-4464368-A | 7-(2-(2-AMINOTHIAZOL-4-YL)-2-(CARBOXY-ALK-2-OXYIMINO)ACETAMIDO) -3-((2-ALKYL-PYRAZOLINIUM-1-YL)METHYL)CEPHEM-4-CARBOXYLATES | GLAXO GROUP LIMITED (GB) | 1984-08-07 | — | — | US | disclosed |