Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 7/20 | 0.54 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12116459 | 0.89 | CCR10 (0.51) | CCR10 | |
| SCHEMBL1312251 | 0.89 | CCR10 (0.51) | CCR10 | |
| SCHEMBL1312253 | 0.89 | CCR10 (0.51) | CCR10 | |
| SCHEMBL12116451 | 0.89 | CCR10 (0.51) | CCR10 | |
| SCHEMBL1312752 | 0.89 | CCR10 (0.51) | CCR10 | |
| SCHEMBL1075484 | 0.86 | CCR10 (0.56) | CCR10 | |
| SCHEMBL12116474 | 0.86 | CCR10 (0.56) | CCR10 | |
| SCHEMBL1076198 | 0.86 | CCR10 (0.56) | CCR10 | |
| SCHEMBL1075485 | 0.86 | CCR10 (0.56) | CCR10 | |
| SCHEMBL12116471 | 0.86 | CCR10 (0.56) | CCR10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276731-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | Boehringer Ingelheim International GmbH (DE) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009126675-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |