Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029398 | 0.91 | TTR (0.39) | TTRTACR1RIPK1CYP1A2CYP3A4 | |
| SCHEMBL10837667 | 0.90 | TACR1 (0.42) | TTRTACR1RIPK1LPAR1LPAR5 | |
| SCHEMBL10837405 | 0.88 | TTR (0.37) | TTRTACR1RIPK1CYP1A2CYP3A4 | |
| SCHEMBL10837117 | 0.88 | NPC1 (0.38) | TTRTACR1RIPK1CYP2C9LPAR1 | |
| SCHEMBL9558577 | 0.87 | TTR (0.36) | TTRTACR1SLC6A4HTR2AKCNH2 | |
| SCHEMBL10837586 | 0.87 | TACR1 (0.37) | TTRTACR1RIPK1LPAR1LPAR5 | |
| SCHEMBL10837451 | 0.87 | TACR1 (0.37) | TTRTACR1RIPK1LPAR1LPAR5 | |
| SCHEMBL9557873 | 0.87 | NR4A1 (0.38) | TTRTACR1RIPK1LPAR1LPAR5 | |
| SCHEMBL10837314 | 0.87 | HTR2A (0.38) | TTRTACR1RIPK1LPAR1LPAR5 | |
| SCHEMBL10836254 | 0.86 | TTR (0.36) | TTRTACR1SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |