Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 3/20 | 0.42 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238503 | 1.00 | HRH1 (0.44) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL11238496 | 1.00 | HRH1 (0.44) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL7081665 | 1.00 | HRH1 (0.44) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL10839843 | 1.00 | HRH1 (0.44) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| Fumaric Acid SCHEMBL10839429 | 0.89 | HRH1 (0.42) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| Fumaric Acid SCHEMBL10839432 | 0.89 | HRH1 (0.42) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| Fumaric Acid SCHEMBL10839421 | 0.89 | HRH1 (0.42) | HRH1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL11235738 | 0.84 | HRH1 (0.53) | HRH1SLC6A4SLC6A2SLC6A3GBA1 | |
| SCHEMBL19050113 | 0.84 | HRH1 (0.53) | HRH1SLC6A4SLC6A2SLC6A3GBA1 | |
| SCHEMBL11235745 | 0.84 | HRH1 (0.53) | HRH1SLC6A4SLC6A2SLC6A3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585785-A | HYPOTENSIVES, ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1986-04-29 | — | — | US | disclosed |
| US-4452809-A | ANTIARRHYMIA, HYPOTENSIVE AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1984-06-05 | — | — | US | disclosed |