Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172029 | 0.87 | CSNK2A1 (0.50) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL2170731 | 0.87 | PDE4B (0.53) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL13304018 | 0.85 | PDE4B (0.46) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL38661070 | 0.81 | PDE4B (0.41) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL2848037 | 0.80 | PDE4B (0.52) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL10409117 | 0.79 | PDE4B (0.42) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL9688854 | 0.79 | PDE4B (0.47) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL3128212 | 0.78 | PDE4B (0.46) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL20327434 | 0.78 | PDE4B (0.46) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL3118083 | 0.77 | PDE4B (0.50) | PDE4BPDE3APDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581349-A | Certain benzodiimidazoles and their use as radiation sensitizers | UNIVERSITY OF MARYLAND (US) | 1986-04-08 | — | — | US | disclosed |