Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848024 | 0.95 | PDE3B (0.46) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10842499 | 0.95 | PDE3B (0.46) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10841991 | 0.94 | PDE3B (0.46) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10844891 | 0.94 | PDE3B (0.46) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10844664 | 0.94 | PDE3B (0.46) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10846795 | 0.93 | PDE3B (0.47) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10845945 | 0.91 | PDE3B (0.45) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10845174 | 0.91 | PDE3B (0.45) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10845613 | 0.90 | PDE3B (0.53) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10844568 | 0.89 | PDE3B (0.47) | PDE3BPDE3ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593029-A | Enzyme inhibitor | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |