Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844431 | 1.00 | MAPT (0.46) | MAPTALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL10842188 | 1.00 | MAPT (0.46) | MAPTALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL10842144 | 1.00 | MAPT (0.46) | MAPTALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL10849738 | 0.99 | MAPT (0.47) | MAPTALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL8702336 | 0.94 | MAPT (0.47) | MAPTALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL10848726 | 0.92 | MAPT (0.47) | MAPTALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL2443194 | 0.88 | MAPT (0.53) | MAPTALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL7317041 | 0.86 | MAPT (0.42) | MAPTALDH1A1KDM4ESIRT5BACE1 | |
| SCHEMBL7321233 | 0.86 | MAPT (0.42) | MAPTALDH1A1KDM4ESIRT5BACE1 | |
| SCHEMBL13900803 | 0.86 | MAPT (0.57) | MAPTALDH1A1LMNAKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593029-A | Enzyme inhibitor | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |