Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596955 | 1.00 | TDP1 (0.58) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL684168 | 0.91 | TDP1 (0.51) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11298456 | 0.91 | TDP1 (0.58) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10945541 | 0.91 | TDP1 (0.58) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10980073 | 0.91 | TDP1 (0.58) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10948884 | 0.90 | TDP1 (0.49) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10952968 | 0.90 | TDP1 (0.47) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10530026 | 0.90 | TDP1 (0.47) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL13825275 | 0.90 | TDP1 (0.47) | TDP1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10532299 | 0.90 | TDP1 (0.47) | TDP1LMNACYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H49-H | Process for producing 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylates | FMC CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |