Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL10844685 | 0.83 | HSP90AA1 (0.49) | HSP90AA1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9835984 | 0.77 | KMT2A (0.46) | HSP90AA1CYP19A1CYP3A4KMT2AMEN1 | |
| SCHEMBL10817596 | 0.75 | HSP90AA1 (0.50) | HSP90AA1CYP19A1KMT2AMEN1MAPT | |
| SCHEMBL9451769 | 0.73 | HSP90AA1 (0.45) | HSP90AA1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10843629 | 0.69 | CYP3A4 (0.43) | HSP90AA1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10848166 | 0.69 | CYP3A4 (0.43) | HSP90AA1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10363437 | 0.68 | CYP3A4 (0.40) | HSP90AA1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10842189 | 0.66 | HSP90AA1 (0.45) | HSP90AA1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10365822 | 0.65 | HSP90AA1 (0.61) | HSP90AA1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9834532 | 0.64 | MAPT (0.47) | HSP90AA1CYP19A1CYP3A4KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609668-A | AGRICULTURE | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | disclosed |