Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841238 | 0.71 | KDM4E (0.30) | LMNA | |
| SCHEMBL3862997 | 0.62 | MAPK1 (0.39) | MAPTCCR2 | |
| SCHEMBL10844886 | 0.62 | CRBN (0.32) | — | |
| SCHEMBL24112225 | 0.60 | CRBN (0.31) | ALDH1A1 | |
| SCHEMBL24112723 | 0.60 | CRBN (0.31) | ALDH1A1 | |
| SCHEMBL10841010 | 0.60 | — | — | |
| SCHEMBL17007220 | 0.59 | — | — | |
| SCHEMBL23975737 | 0.59 | BLM (0.31) | MEN1LMNAKMT2A | |
| SCHEMBL24112818 | 0.58 | — | — | |
| SCHEMBL9093338 | 0.58 | CA1 (0.35) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4577023-A | Diazabicyclo (2,2,2) octadiones | STAMICARBON B.V. (NL) | 1986-03-18 | — | — | US | claimed |
| US-4577023-A | Diazabicyclo (2,2,2) octadiones | STAMICARBON B.V. (NL) | 1986-03-18 | — | — | US | disclosed |
| EP-0080245-A1 | Diazabicyclo(2,2,2)octadiones and process for their preparation | STAMICARBON B.V. (NL) | 1983-06-01 | — | — | EP | disclosed |