Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.66 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845603 | 0.99 | PDE3B (0.65) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10843137 | 0.99 | PDE3B (0.65) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10844882 | 0.99 | PDE3B (0.65) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10843923 | 0.97 | PDE3B (0.67) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10845172 | 0.94 | PDE3B (0.65) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10847199 | 0.89 | PDE3B (0.65) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10843825 | 0.88 | PDE3B (0.64) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10845543 | 0.88 | PDE3B (0.64) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10843208 | 0.88 | PDE3B (0.64) | PDE3BPDE3AP2RY12 | |
| SCHEMBL10841744 | 0.88 | PDE3B (0.64) | PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593029-A | Enzyme inhibitor | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |