SCHEMBL10847

SCHEMBL10847

O=C1CCc2ccccc2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 1.00
CYP1A2 P05177 2/20 0.70
CES1 P23141 2/20 0.48
ANPEP P15144 4/20 0.47
TSHR P16473 1/20 0.46
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
CYP2C19 P33261 1/20 0.44
DRD2 P14416 1/20 0.44
DRD1 P21728 1/20 0.44
DRD4 P21917 1/20 0.44
DRD5 P21918 1/20 0.44
DRD3 P35462 1/20 0.44
MAOA P21397 2/20 0.42
NPC1 O15118 1/20 0.41
MAPK13 O15264 1/20 0.41
MAPK12 P53778 1/20 0.41
MAPK11 Q15759 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411939 1.00 CYP2A6 (1.00) CYP2A6CYP1A2CES1ANPEPTSHR
SCHEMBL467668 0.86 CYP2A6 (0.75) CYP2A6CYP1A2CES1ANPEPTSHR
SCHEMBL12205504 0.85 CYP2A6 (0.74) CYP2A6CYP1A2CES1ANPEPTSHR
SCHEMBL379443 0.85 CYP2A6 (0.74) CYP2A6CYP1A2CES1ANPEPTSHR
SCHEMBL30040379 0.83 CYP2A6 (0.71) CYP2A6CYP1A2CES1CYP2C19MAOA
SCHEMBL77106 0.83 CYP1A2 (1.00) CYP2A6CYP1A2CES1ANPEPTSHR
SCHEMBL29366435 0.83 CYP1A2 (1.00) CYP2A6CYP1A2CES1ANPEPTSHR
Acetophenone SCHEMBL28196430 0.81 CYP2A6 (0.66) CYP2A6CYP1A2CES1NPC1HPGD
Ammonia Solution, Strong SCHEMBL13736473 0.80 CYP1A2 (0.94) CYP2A6CYP1A2CES1ANPEPTSHR
SCHEMBL10463768 0.80 CYP1A2 (0.94) CYP2A6CYP1A2CES1ANPEPTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2497 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118956991-B Synthesis method of chiral amine 天津凯莱英生物科技有限公司 2025-03-07 CN claimed
CN-119306681-A Synthesis method of 3-oxazoline-5-ketone and derivative thereof 湖南医药学院 2025-01-14 CN claimed
CN-109851549-B 5-hydrogen-benzo [ b ] carbazole and related derivatives and synthetic method thereof 西安欧得光电材料有限公司 2022-03-29 CN claimed
US-11248138-B2 Printing ink formulations, preparation methods and uses thereof GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-02-15 US claimed
CN-109678788-B 1, 2-diaryl indole, derivative and synthetic method thereof 湘潭大学 2021-05-04 CN claimed
CN-107619386-B Aromatic ring [ c ] carbazole derivative and synthesis method thereof 湘潭大学 2020-10-13 CN claimed
CN-108047156-B 5-methylmorpholine-3-amino-2-oxazolidinyl ketone antigen with spiro structure, antibody, preparation and application 华南农业大学 2020-08-07 CN claimed
CN-105038408-B Printing ink and electronic device printed by using same 广州华睿光电材料有限公司 2020-01-07 CN claimed
CN-107418556-B A kind of fluorescence probe and its preparation method and application detecting hydrogen sulfide 济南大学 2019-10-25 CN claimed
EP-3546532-A1 PRINTING INK COMPOSITION, PREPARATION METHOD THEREFOR, AND USES THEREOF Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2019-10-02 EP claimed
EP-0385658-B1 Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes LILLY CO ELI (US) 1994-12-28 EP claimed
WO-1994007863-A9 OCTAHYDRONAPHTHOQUINOLIZINES, AND METHODS OF MAKING AND USING THEREOF 1994-06-09 WO claimed
WO-1994007863-A1 OCTAHYDRONAPHTHOQUINOLIZINES, AND METHODS OF MAKING AND USING THEREOF NEW YORK UNIVERSITY (US) 1994-04-14 WO claimed
US-4966975-A Processes for the preparation of novel naphthalenylmethyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents AMERICAN HOME PRODUCT 1990-10-30 US claimed
EP-0385658-A1 Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes ELI LILLY AND COMPANY (US) 1990-09-05 EP claimed
EP-0168505-B1 SUBSTITUTED 2-AMINOTETRALINS AND PROCESSES FOR SYNTHESIS Whitby Research Incorporated (US) 1989-08-09 EP claimed
EP-0168505-A1 Substituted 2-aminotetralins and processes for synthesis Whitby Research Incorporated (US) 1986-01-22 EP claimed
US-4493904-A COORDINATION, POLYMERIZATION CATALYST CONTAINING TITANIUM TRICHORI CONOCO INC. (US) 1985-01-15 US claimed
US-4374979-A Regiospecific synthesis of anthracyclinone compounds such as daunomycinone THE UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) 1983-02-22 US claimed
EP-0063945-A1 Process for the regiospecific synthesis of anthracyclinone compounds such as daunomycinone THE UNIVERSITY OF KANSAS (US) 1982-11-03 EP claimed