Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | TYR | P14679 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32664321 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL29363877 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL5695407 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL5695433 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10849419 | 0.81 | MAPT (0.51) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10853946 | 0.79 | MAPT (0.89) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10853940 | 0.79 | MAPT (0.89) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10847592 | 0.78 | MAPT (0.71) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10847566 | 0.77 | MAPT (0.81) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10847571 | 0.77 | MAPT (0.81) | MAPTMEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567048-A | SULFONATED INDOXYL DERIVATIVES | PFIZER INC. (US) | 1986-01-28 | — | — | US | disclosed |